Flow-cytometric assessment of lymphocyte cytokine production in tuberculosis (2002) 

M. Garcia, J.A. Vargas, R. Castejón, E. Navas, A. Durantez 

Tuberculosis 82 (1): 37-41

Comparative study on the use of solid media: Lowenstein-Jensen and Ogawa in the determination of anti-tuberculosis drug susceptibility (2002)

S. Tanoue, S. Mitarai, H. Shishido

Tuberculosis 82 (2/3): 63-67

Laboratory diagnosis of Mycobacterial infections (2000)

David F. Gardiner and Kathleen G. Beavis

Seminars in Respiratory Infections 15 (2): 132-143

Lipid domains of mycobacteria studied with fluorescent molecular probes (1999)

Henriette Christensen, Natalie J. Garton, Richard W. Horobin, David E. Minnikin and Michael R. Barer

Molecular Microbiology 31 (5): 1561-1572

Synergistic activities of clarithromycin and antituberculous drugs against multidrug-resistant Mycobacterium tuberculosis (1995)

Stephen J. Cavalieri, Jon R. Biehle and W. Eugene Sanders, Jr

Antimicrobial Agents and Chemotherapy 39(7): 1542-1545

Analysis for a Limited Number of Gene Codons Can Predict Drug Resistance of Mycobacterium Tuberculosis in a High - Incidence Community (2001)

Annelies Van Rie, Robin Warren, Idris Mshanga, Annemarie M Jordan, Gian D. Van Der Spuy, Madalene Richardson, John Simpson, Robert P. Gie, Donald A. Enarson, Nulda Beyers, Paul D. Van Helden and Thomas c. Victor

Journal of Clinical Microbiology 39(2): 636-641

In vitro inhibition of drug-resistant and drug sensitive strains of Mycobacterium tuberculosis by ethnobotanically selcted South African plants (1999)

N. Lall, J.J.M. Meyer

Journal of Ethnopharmacology 66: 347-354

Mycobacterial Growth Indicator Tube fro Susceptibility Testing of Mycobacterium tuberculosis to Isoniazid and Rifampin (1997)

John S. Bergmann and Gail L. Woods

Diagn Microbiol Infect Dis 27: 153-156

Use of Genomics and Combinatorial Chemistry in the Development of New Antimycobacterial Drugs (2000)

Clifton E. Barry, III, Richard A. Slayden, Andrea E. Sampson and Richard E. Lee

Biochemical Pharmacology 59: 221-231

The genetics and biochemistry of isoniazid resistance in Mycobacterium tuberculosis (2000)

Richard A. Slayden, Clifton E. Barry, 3rd

Microbes and Infection 2: 659-669

Prospects for development of new antimycobacterial drugs (2000)

Haruaki Tomioka

J Infect Chemother 6:8-20

Activities of Isoniazid Alone and in Combination with Other Drugs against Mycobacterium avium Infection in Beige Mice ( 1998)

Lanfranco Fattorini, Yan Xiao, Maurizio Mattei, Yongjun Li, Elisabetta Iona, Maria Luisa Ricci, Ove Fredrik Thoresen, Roberta Creti and Graziella Orefici

Antimicrobial Agents And Chemotherapy 42(3): 712-714

Molecular Epidemiology of Tuberculosis in Malaysia (1999)

Jeremy W. Dale, Rohana Mat Nor, Soshila Ramayah, Thean Hock Tang and Zainul F. Zainuddin

Journal of Clinical Microbiology 37(5): 1265-1268

The nonenzymatic activation of isoniazid by Mn III – pyrophosphate in the presence of NADH produces the inhibition of the enoyl-ACP reductase InhA from Mycobacterium tuberculosis (2001)

Michel Nguyen, Annaik Quemard, Hedia Marrakchi, Jean Bernadou, Bernard Meunier

C.R.Acad. Sci. Paris , Chemistry 4:35-40

Antimycobacterial activity of new ortho-, meta, and para-toluidine derivatives (1999)

Mariangela Biava, Rosella Fioravanti, Giulio Cesare Porretta, Giancarlo Sleiter, Deila Dedda, Giorgio Lampis, Raffaello Pompei

Synthesis and antimycobacterial activity of some isonicotinoylhydrazones (1999)

Maria T. Cocco, Cenzo Congiu, Valentina Onnis, Maria C. Pusceddu, Maria L. Schivo, Alessandro De Logu  

The Need for New Drugs against Tuberculosis (2001)

Richard J. O'Brien and Paul P. Nunn

Am J Respir Crit Care Med 162:1055-1058

Measurement of Sputum Mycobacterium tuberculosis Messenger RNA as a Surrogate for Response to Chemotherapy (1999)

Lucy E. Desjardin, Mark D. Perkins, Kathy Wolski, Shirley Haun, Lucileia Teixeira, Ying Chen, John L. Johnson, Jerrold J. ellner, Reynaldo Dietze, Joseph Bates, M. Donald Cave and Kathleen D. Eisenach

Am J Respir Crit Care Med 160:203-210

Novel Mutations in ndh in Isoniazid-Resistant Mycobacterium tuberculosis Isolates (2001)

Ann S. G. Lee, Audrey S. M. Teo and Sin-Yew Wong

Antimicrobial Agents and Chemotherapy 45(7):2157-2159

Use of Real-Time PCR and Fluorimetry fro Rapid Detection of Rifampin and Isoniazid Resistance-Associated Mutations in Mycobacterium tuberculosis (2000)

Contribution of kasA Analyssis to detection of Isoniazid-Resistant Mycobacterium tuberculosis in Singapore (1999)

Ann S.G. Lee, Irene H. K. lim, Lynn L. H. Tang, Amalio Telenti and Sin Yew Wong

Antimicrobial Agents and Chemotherapy 43(8):2087-2089

Microarrays fro public health: genomic epidemiology of tuberculosis (2002)

Jamila Shafi, Peter W. Andrew and Michael R. Barer

Comparative and Functional Genomics 3:362-365

Evolutionary genomics of pathogenic bacteria (2001)

J. Ross Fitzgerald and James M. Musser

TRENDS in Microbiology 9(11):547-553

Tuberculosis Drug Targets (2002)

Ying Zhang and L. Mario Amzel

Current Drug Targets 3:131-154

Recent bioequivalence studies on fixed-dose combination anti-tuberculosis drug formulations available on the global market (1999)

Pillai G, Fourie PB, Padayatchi N, Onyebujoh PC, McIlleron H, Smith PJ, Gabriels G

Int J Tuberc Lung Dis 3(11 Suppl 3):S309-321

Characterization of isoniazid-resistant strains of Mycobacterium tuberculosis on the basis of phenotypic properties and mutations in katG (2001)

Abate G, Hoffner SE, thomsen VO, Miorner H Eur J Clin

Comparing Genomes within the Species Mycobacterium tuberculosis (2001)

Midori Kato-Maeda, Jeanne T. Rhee, Thomas R. Gingeras, Hugh Salamon, Jorg

Drenkow, Nat Smittipat and Peter M. Small

Genome Research 11:547-554

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Action Mechanism of Antitubercular Isoniazid (2000)

Benfang Lei, Chih-Jen wei and Shiao-Chun Tu

Then Journal of Biological Chemistry 275(4):2520-2526

Molecular Diagnosis of Drug Resistant Tuberculosis (2001)

Suhail Ahmd, abu Salim Mustafa

Kuwait Medical Journal 33(2):120-126

Microbial Pathogenesis of Mycobacterium tuberculosis: Dawn of a Discipline (2001)

Michael S. Glickman and William R. Jacobs

Cell 104:477-485

Genetic Detection of Antimycobacterial Resistance (2001)

Franklin R. Cockerill, III

ISAAR 2001: 245-259

The molecular basis of resistance to isonoazid, rifampin and pyrazinamide in Mycobacterium tuberculosis (2001)

Akos Somoskovi, Linda M Parsons and Max Salfinger

Respiratory  Research 2:164-168  

Molecular Approaches to Tuberculosis (2001)

Jose A Ainsa, Carlos Martin and Brigitte Gicquel

Molecular Microbiology 42(2):561-570

Drug Resistant and multidrug-resistant tubercle bacilli (1999)

Bjorn Petrini, Sven Hoffner

International Journal of Antimicrobial Agents 13:93-97

Modification of the NADH of the Isoniazid Target (InhA) from Mycobacterium tuberculosis (1998)

Denise A. Rozwarski, Gregory A. Grant, Derek H. R. Barton, William R. Jacobs Jr., James C. Sacchettini

SCIENCE 279:98-102

Crystal Structure of the Mycobacterium tuberculosis Enoyl-ACP Reductase, InhA, in Complex with NAD+ and a C16 Fatty Acyl Substrate (1999)

Denise A. Rozwarski, Catherine Vicheze, Michele Sugantino, Robert Bittman and James C. Sacchettini

Significance of ahpC Promoter Mutations for the Prediction of Isoniazid Resistance in Mycobacterium tuberculosis (1998)

H.Rinder, A. Thomschke, S. Rusch-Gerdes, G. Bretzel, K. Feldmann, M. Rifai, T. Loscher

Determination of the primary target for isoniazid in mycobacterial mycolic acid biosynthesis with Mycobacterium arum A+(1996)

Paul R. Wheeler and Paul M. Anderson

Biochem J 318:451-457

Characterization of the Mycobacterium tuberculosis H37Rv alkyl hydroperoxidase AhpC points to the importance of ionic interactions in oligomerization and activity (2001)

Radha Chauhan and Shekar C. Mande

Biochem J 354:209-215

Use of site-directed mutagenesis to probe the structure, function and isoniazid activation of the catalse/peroxidase, KatG, from Mycobacterium tuberculosis (1999)

Brigitte Saint-Joanis, Helena Souchon, Martin Wilming, Kai Johnson, Pedro M. Alzari and Stewart T. Cole

Biochem J 338:753-760

Isoniazid affects multiple components of the type II fatty acid synthase system of

Mycobacterium tuberculosis (2000)

Richard A. Slayden, Richard E. Lee and Clifton E. Barry, 3rd

Molecular Microbiology 38(3):514-525

KATG/TB Dr. Habibah

Isoniazid Accumulation in Mycobacterium smegmatis Is Modulated by Proton Motive Force-Driven ATP Dependant Extrusion Systems (1999)

Baisakhee Saha Choudhuri, Susmita Sen and Parul Chakrabarti

Biochemical and Biophysical Research Communications 256:682-684  

Characterization of the katG and inhA Genes of Isoniazid-resistant Clinical Isolates of Mycobacterium tuberculosis (1995)

David A Rouse, Zhongming Li, Gil-Han Bai, and Sheldon L. Morris

Antimicrobial Agents and Chemotherapy 39(11):2472-2477

Safe Determination of Susceptibility of Mycobacterium tuberculosis to Antimycobacterial Agents by Flow Cytometry (1999)

Andrea V. Moore, Scott M. Kirk, Steven M. Callister, Gerald H. Mazurek and Ronald F. Schell

Journal of Clinical Microbiology 37(3):479-483

Spread of Drug Resistant Pulmonary Tuberculosis in Estonia (2001)

Annika Kruuner, Sven E. Hoffner, Heinart Sillastu, Manfred Danilovits, Klavdia Levina,

Stefan B. Svenson, Solomon Ghebremichael, Tuija Koivula and Gunilla Kallenius

Journal of Clinical Microbiology 39(9);3339-3345

Molecular Evidence for Heterogeneity of the Multiple-Drug-Resistant Mycobacterium

tuberculosis Population in Scotland (1990 to 1997) (1999)

Z. Fang, C. Doig, A. Rayner, D.T. Kenna, B. Watt and K.J. Forbes

Journal of Clinical Microbiology 37(40):998-1003

Multidrug-Resitant Mycobacterium tuberculosis: Molecular perspectives (1998)

Ashok Rattan, Awdhesh Kalia and Nishat Ahmad

Emerging Infectious Diseases 4(2):195-209

Kat G Mutations in Isoniazid-Resistant Strains of Mycobacterium tuberculosis Are Not Infrequent (1996)

T.C. Victor, G.S. Pretorius, J.V. Felix, A.M. Jordaan, P.D. van Helden and K.D. Eisenach

Antimicrobial Agents and Chemotherapy 40(6):1572

Molecular Analysis of katG Gene Mutations in Strains of Mycobacterium tuberculosis Complex from Africa (1997)

Walter H. Haas, Kathrin Schilke, Jeanette Brand, Beate Amthor, Karin Weyer, P. Bernard Fourie, Gisela Bretzel, Veronica Sticht-Groh and Hans J. Bremer

Antimicrobial Agents and Chemotherapy 41(7):1601-1603

The Susceptibility of Mycobacterium tuberculosis to Isoniazid and the Arg-Leu Mutation at

Codon 463 of katG Are Not Associated (2001)

H.R. Van Doorn, E.J. Kuijper, A. Van. Der Ende, A.G. A. Welten, D. Van Soolingen, P.E.W. De Haas and J. Dankert

KatG Mutations in Isoniazid-resistant Mycobacterium tuberculosis Isolates Recovered from

Finnish Patients (1996)

Harri J. Marttila, Hanna Soini, Pentti Huovinen and Matti K. Viljanen

Antimicrobial Agents and Chemotherapy 40(9):2187-2189

Mutations in katG Gene Sequences in Isoniazid-Resistant Clinical Isolates of Mycobacterium tuberculosis Are Rare (1995)

G.S. Pretorius, P.D. Van Helden, F. Sirgel, K.D. Eisenach and T.C. Victor

Antimicrobial Agents and Chemotherapy 39(10):2276-2281

Molecular Mechanisms of Isoniazid Resistance in Mycobacterium tuberculosisi and Mycobacterium bovis (1995)

David A. Rouse and Sheldon L. Morris

Infection and Immunity 63(4):1427-1433

Characterization of the katG and inhA Gene of Isoniazid-resistant Clinical Isolates of

Mycobacterium tuberculosis (1995)

David A. Rouse, Zhongming Li, Gil-Han Bai and Sheldon L. Morris

Antimicrobial Agents and Chemotherapy 39(11):2472-2477

A Ser315Thr Substitution in KatG Is Predominant in Genetically Heterogenous Multidrug-

Resistant Mycobacterium tuberculosis Isolates Originating from the St. Petersburg Area in

Russia (1998)

Harri J. Marttila, Hanna Soini, Erkki Eerola, Elena Vyshnevskaya, Boris I. Vyshnevskiy,

Tatjana F. Otten, Alexandr V. Vasilyef and Matti K. Viljanen

Antimicrobial Agents and Chemotherapy 42(9):2443-2445

New Real-Time PCR Able To Detect in a Single Tube Multiple Rifampin Resistance Mutations and High Level Isoniazid Resistance Mutations in Mycobacterium tuberculosis (2002)

Bario Garcia de Viedma, Maria del Sol Diaz Infantes, Fatima Lasala, Fernando Chaves, Luis Alcala and Emilio Bouza

Journal of Clinical Microbiology 40(3):988-995

Novel Selection for Isoniazid (INH) Resistance Genes Supports a Role for NAD+ - Binding Proteins in Mycobacterial INH Resistance (1998)

Ping Chen and William R. Bishai

Infection and Immunity 66(11):5099-5106

Analysis for a Limited Number of Gene Codons Can Predict Drug Resistance of

Mycobacterium tuberculosis in a High-Incidence Community (2001)

Annelies Van Rie, Robin Warren, Idris Mshanga, Annemarie M Jordaan, Gian D. Van Der Spuy, Madalene Richardson, John Simpson, Robert P. Gie, Donald A. Enarso, Nulda Beyers, Paul D. Van Helden and Thomas C. Victor

Genomics and Antimicrobial Drug Discovery (1999)
Donald T. Moir, Karen J. Shaw, Roberta S. Hare and Gerald F. Vovis
Antimicrobial Agents and Chemotherapy 43(3):439-446